I say yes! 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Gave my dogs simparica and they both have lost their appetite! His intestines are still bleeding and he is not responding to therapy that should have resolved the diarrhea by now. Has odd agitated swallowing when not eating anything. stares off into space with reduced blinking. He had ONE dose that evening and completely lost his appetite within a couple days. According to the email I received today, Simparica starts killing ticks in 8 hours and is >96.9% effective for 35 days against weekly reinfestations of the above named ticks. Our Pickles died last year after just 3 doses, and our vet basically said we were crazy. I’m certain that it’s the simparica. First time for this adverse reaction. It's definitely not! Her heartbeat was more of a vibration than a beat and the vet wanted her to see a cardiologist. Our dog has not been given another dose. Simparica (sarolaner) Chewables are safe, monthly flea and tick protection for dogs that start working fast and remain effective all month long. Seizures continue and it’s Monday. Last month she had diarrhea and it lasted 7 days. 1 is pregnant I told the vet what can I give the pregnant yorkie she said sampirica sold me a 3 month supple for her. Or crush them up and add them to his feed, but with the simparica chews it swallowed them straight away. I gave our boy, Yogi his first dose of Simparica TRIO on 11/17/2020. Hi Laura, just wondering what supplements you gave your pup to help and how long it took for her to get back to herself after simparica. This Tuesday the 17th I had given my dog simparica trio for 27lbs dose. The big question is. I can’t imagine how horrible a whole dose would have been. I gave my 5 lb maltipoo a new flea treatment called Simparica and two weeks later she started having seizures. No running or jumping, Continuously wandering around the fence line of the back yard. She is only 6 and was so full of life and energy. It is important to make sure that the right product is used, the FDA said. The representative for the company says the half life is 16 days. The vet won’t acknowledge it was Simparica although Dolly had no problems with seizures before. We did skin scrape and they kept saying allergies. Simparica is for use only in dogs, 6 months of age and older. Never had them ever and she's only 3 1/2 yrs old. No side effects. It is now day 18 since his last dose of Simparica and he looks good on the outside but has a very selective appetite and has dark black watery diarrhea still but now with some red blood in the stool. We gave our Austrailian Cattle Dog 1 dose of Simparica. And im so mad that my vet didn't inform me of the side effects and im so mad I didn't research it myself. }); Simparica for Dogs Cost, Side effects, Reviews, Safety. 小狗; 貓; 品牌 . After her first dose she had diarrhea, vomiting and developed a terrible wheezing hacking cough. I will never give another dose to him! We all want to protect our pets from fleas, ticks and the diseases they carry, but some treatments can come with nasty side effects. I stressed that I dislike putting toxins in my dogs body. Advised I could call Simparica for reimbursement or to report side effects. The biopsy report is pending. As she improves her compromised development will need to be addressed. The vet just gave our 16lb shorkie this on Tuesday and he still has the tremors really bad and very lethargic, I’m very worried and concerned. My husband said that he felt like it would just make his coat shiny. We think that the drug is the cause of the seizures . Please advise! I gave my precious puppy this and 12 hours later. Not long after ingesting the chewable she began to have tremors, but not full blown seizures. What is Simparica Trio? The results are fatal for fleas and ticks but safe for mammals such as your dog. Does this sound familiar to anyone? My dog has been vomiting with diarrhea plus he has bumps all over his body from one dose of simparica trio. I am sorry you are going through this! Our new vet has recommended Simperica, but I won’t be giving it to my Collie. I've spoken to emergency vets and they say they are booked solid and that I need to just monitor her through the night. Simparica is available as a liver-flavored, chewable tablet. Omg I’m feeling sick seeing all these bad comments. She has had tremors, very lethargic, drinking lots of water. My Labradoodle had extreme diarrhea last night. Our pups had been on next guard and heart guard with no issues but new vet stopped selling those products so switched to to the simparica trio - gave a dose to our 7 ur old 71 pound blue tick coonhound Frazier and our 10 mo 45 pound labradoodle- Watson. Follow up: my Labradoodle visited the ER on T-Day for 2 hrs. Thanks to its innovative formula, the treatment continues to work for 35 days, providing long-lasting relief from parasites and the diseases they carry. Vets at Petsmart should know better; changing vets. I don't recommend anyone risk their pet's life just to be a little easier having a pill to take. They must get some kind of monetary bonus for only selling Simparica. Simparica (sarolaner) Chewables are safe, monthly flea and tick protection for dogs that start working fast and remain effective all month long. Kind of ooze. All oral tick meds are a risk. I feel so bad ,my 8weeks cockerspaniel hasn’t been the same 24 hours of giving first dose of Simparica trio.My boy has been distressed with lethargic conditions,sleepy and peeing . I'll continue to watch her. Even when asked to go for a car ride he didn't respond. Disregard cleared up in three days, I finished the 7 day prescription. Head down, tail down, will stand in a corner and stare at the wall. Do not use on breeding, pregnant or lactating bitches or dogs as the safety studies have not been done. like she wants me to fix it. After he was sent home, he was still not well and barely able to hold in any food and had to take any fluids intravenously. He has had a barium series that showed no foreign bodies and endoscopy which showed hemorrhages in the stomach and upper bowel. This past October he just wasn't the same. She’s not the carefree setter she was prior to this medication. One says, “It is a great product. My 7 month old male Goldendoodle developed vomiting of digested blood 4 days after Simparica and the following day developed black tar like stools of digested blood. Won’t use again. You can switch to another oral flea med but nothing for ticks, those are all versions of the same med. Manufacturer claims that the dog is safe for long-term consumption as long as the owner administers the proper dosage. Do you have a homeopathic vet in your area? They are doing mucus runny poos and my adult poodle now has blood in her poo. Here are 3 of the top hormone pellet side effects that you may encounter: Tenderness – BioTE® pellet therapy is inserted into the gluteal area. The only thing the vet told me was that his ATL liver enzyme levels were just slightly high (170) and it wasn't a concern and we could just do another blood test at his next check-up. These are classic neurological symptoms, exactly what our Pickles had before she passed. On Jan 4th for the first time. Thanks to its innovative formula, the treatment continues to work for 35 days, providing long-lasting relief from parasites and the diseases they carry. I gave it to her then I looked at the box that said never tested on pregnant dogs . I quit the canned sweet potatoes (he loved them) thinking it was the syrup, that I drained anyway before adding to mixture. Collies can tolerate both Simparica and Bravecto. This is happening now and she is still nowhere near 100% but I am hopeful that she will eventually fully recover. Simparica is available in different doses for dogs 2.8 pounds and over, but has not been evaluated for use in pregnant, breeding or nursing pets. Simparica Trio and Simparica are suitable for dogs from 8 weeks of age. I hope this drug has not caused permanent damage. Gave my dog Charlie Simparica yesterday now he is shaking and panting really bad. He has neurological issues from using it, just one time. This is lethal medication for dogs and should be taken off the market now. 6 Pack is of $52.34, Simparica Chewables for Dogs 5.6-11 lbs (Purple) Again, side effects are rare, but they’re usually tied to digestive issues. Also what made you determine it was the flea medication? I called the vet and she gave me anitdiarrhea medicine. DO NOT USE SIMPARICA on any animal. My 5 year old, healthy Australian Shepherd had a check-up + boosters at the vet on January 24th. 6 Pack is of $68.42. And shocked that my Vet has glossed over even the remotest possibility that this particular puppy just might not be able to tolerate this DRUG!!! Simparica is available by prescription only, so discuss any history your dog has of seizure disorders with your veterinarian when determining the best flea and tick treatment for your pet. This crap is poison! Gave our Bloodhound Simparico Trip on Tuesday on Thursday he got extremely thirsty and was peeing everywhere from drinking so much water. Symptoms have increased over the last few weeks, including loss of muscle/body coordination, especially in the morning. After realizing that the only thing that we did differently was to give him his first dose of Simperica, my wife began research and came across this conversation. I'm so glad I found this forum, it confirmed my instincts that this drug is very harmful. Gave Simparica yesterday and am suspect. Simparica is orally administered to dog that are 6 months of age or older and weighing more than 2.8lbs. Simparica for dogs 5 - 10kg Could it have been something else?? Skin issues. The very next day he had diarrhea, and had it for 6 days. Still waiting to find out of she has progressed. He prescribed 7 day dose of Panacur. Snores like a big dog. I wish I could get it out of her system. She hasn't had any of the diarrhea or eating issues, but has had one of her eyes that gets red and the inner eyelid partially covers her pupil. This may post twice - I didn't see my original post so I'm trying again! My dog was HEALTHY and HAPPY prior to giving him this drug and literally days later he is struggling to recover. 9/15, we skipped the dog show this weekend. Today was my 14 year old Jack Russell's 2nd dose of Simparica, her name is Rallye. Hopefully, there is no permanent damage to his brain or body. But the wandering and "head pressing" it's called, where they just go into the corner or lean against a table leg or the wall. This is terrible. That night woke me up with diarrhea. Every drug has side effects. Not drinking any water but drooling and swallowing all the time. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. My wife and I didn't understand why. Spotting Hormone Pellet Side Effects. I have my 14 week old pup simparica (vet recommended) 2 days ago. She will not get this anymore. I even told them about the Simparica which they don’t respond to. 3 Pack is of $34.13 She is lethargic and doesn’t want to eat. Never happened before. How is your dog now? I will never give this again! We are experiencing the same thing. On Friday he was incredibly thirsty - he would drink a full bowl of water and then look at me for more. Good appetite but seizures cause her to fall...Dr says: leash walks, keep kenneled or confined in small room, no playing for 7-10 days and see what happens ???? I don’t know what to do to get this out of their system?? She continued to have seizures even she was on phenobarbital. 6 Pack is of $58.93, Simparica Chewables for Dogs 2.8-5.5 lbs (Yellow) He also, Thank you. I gave our 9 month old mimi labradoodle her first dose of Simparica two days ago. My 14 year old, 3.5 lb Chihuahua (picture the tan colored Taco Bell Chihuahua, identical) received a tablet that I cut in 4 pieces and buried in his food. Because this ingredient works differently on invertebrates than mammals, however, Simparica for dogs has been proven safe during field trials. Prednisone helped symptoms in our case but the seizures kept going even after stopping this horrible med. Simparica requires a prescription from your veterinarian. GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. Some possible side effects of taking Simparica Trio may include : vomiting, diarrhea, lethargy, anorexia, polyria, hyperactivity or polydypsia. It went away, I thought the diarrhea was from some of the junk she eats off of the ground. One monthly dose of Simparica Trio provides triple protection against fleas and ticks, intestinal worms and deadly heartworm. Today, he wouldn't eat or drink any water. I PRAY that our baby is okay with this second dose. I am up writing this 4 a.m. since our Lambchop is too restless to sleep! Are their enough people to file a class action suit? Then she started having tremors. Now instead of solid stools they are watery. Plan to take him to see the vet tomorrow. Sometimes I think he is either blind or deaf. She's been given this dosage for over a year. The Maltese mix is lethargic and won’t jump on bed or couch. Losing my Dolly devastated me and I wanted to warn others about Simparica but I got sick. for flea and ticks? Very "out of it". I won't be letting this go and I'll be actively pursuing recourse from the manufacturer and vet in any way I can. We have an appt for a skin scraping. Then they come back! Will be back at PetSmart on Monday. I brought him to the vet and they keep trying to say excessive water drinking isn’t a side effect but it’s the only thing that is different that I’ve given my pup. My 5 year old Fox Hound isnow drinking lots of water and urinating in the house! My 3 other poodles unaffected. I am very distressed now. This happened the same to my dog.. how si going now with your pet? we gave our dane Simperica Brown about a day or so ago and all the sudden my sweet girl is having seizures. The long side of the prescription form has a ruler with centimeter markings. This drug has caused our dog to loose his footing and not eat. I must admit that I am pretty nervous about it, but we shall see. He will be laying then start shaking all over..Has tremors every 5 minutes for 2 hours now. Simparica comes in a range of sizes and packs for all weight ranges . 1 That gives you a little wiggle room at the end of the month, in case you’re late with the next month’s dose. The initial trial had seizure results but supposedly only in dogs with seizure history. I suppose with any drug, during trials, there will be some who have side effects ranging from negligible to life threatening. The king cavalier bichon mix seems to be ok just not eating much if at all. This is still going on weeks later. Against my better judgement, 9/1 3rd dose of Simparica – that next morning 5am pup had raging liquid diarrhea. Simparica begins to kill adult fleas within 3 hours and ticks within 8 hours of administration. Tremors continued, on and off, for 2 hours. Thru the night thru the day. Our 6 year old, 66# Treeing Walker Coon Hound baby has been taking Simparica for about two years. He was diagnosed with "Sundowners" . I’m switching back to the old stuff. The most frequently reported adverse reactions were vomiting and diarrhea. Exactly. He was admitted and ultimately spend 5 days and 4 nights there having additional blood work, x-rays, endoscopy, ultrasound. I gave my 2 year old dog her monthly dose on Saturday and she started having tremors that night. She is 9 months old, a giant breed puppy who now weighs 61.9 pounds. However, of those dogs that do experience adverse reactions, diarrhea, excessive drool, loss of appetite and vomiting are common. If you need to get rid of parasites, spot-on (the one by a German company is effective enough) will do the job and do it safely. A dog vaccine can sometimes produce adverse side effects. So, I gave it to him. He is acting very skittish/scared like behavior, wants to just lay down. It is the flea and tick component that is the problem. Vet expressed no concerns re Simparica. Will not eat or drink. Today is Friday. This time he is having seizures. No more of this med! Status of your dog after @1 year? This will be a regular purchase for our girl’’. It seems to coincide with the monthly dosage. Simparica Trio. She had terrible watery diarrhea and is not interested in eating. Since then nothing. All went well until this morning. Monday, Tuesday, Wednesday and Thursday he slept all day, was hesitant to get up, wouldn't play with his ball, continued to drink excessively and shivered. He has never acted like he was in pain. I'm at a loss... We had same issues. Protect your pet with the Simparica range. Now her dog is very sick and she has to take the dog to the vet every day in the past week. Eyes roll back. Simparica is only registered for dogs so not use for any other animal. Simparica is a pet medication that treats fleas and ticks. Many can cause nausea, vomiting and neurological side effects. I gave the 1st one to my dog, 1st of this month. Best case scenario, he is able to come home, but we aren't there yet. 9/12 1:30 was last bout of liquid stools. In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. I need to tell my vet to switch! Talk me down people!! Acute pulmonary reactions are commonly manifested by fever, chills, cough, chest pain, dyspnea, pulmonary infiltration with consolidation or pleural effusion on x-ray, and eosinophilia. He just isn’t himself. I would, still boil chicken, carrots, potatoes for his meals. Mike. Uncontrollable seizures in a dog….just horrific to see this dog and what he is going through while his owner is trying to comfort him. He developed these big sores which scab over quickly, hair falling out here and there. Furious that this out there for pets. When I bathe him the scabs fall off and I think, oh good, this problem is going away. Sunday I started watching how much water he was drinking feeling bad that I was restricting him, so I made sure to take him out to pee every few hours. Although he didn’t continue throwing up and was fine otherwise, he was still outside 12 hours later eating grass. No problem eating. But I have heard of other dogs who recover, or who continue having seizures but not fatal. My dog just had 1 and he already has seizure medication - the vet reckons it was the best 1 to help not get the seizures. Simparica (Sarolaner (Simparica™ chewable tablets, Zoetis), is widely used by veterinarians for the treatment and prevention of flea and tick infestations in dogs. I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. When fleas or ticks bite, they are exposed to its FDA-approved ingredient sarolaner, the insecticide, and acaricide that kills parasites fast. My beautiful boxer lost his appetite after just one dose of Simparica. 6 Pack is of $55.36, Simparica Chewables for Dogs 22.1-44 lbs (Blue) Simparica is a fast-acting oral flea and tick preventative that begins killing fleas and ticks within hours of administration and remains effective for one month to prevent re-infestations. Not to worry you, and I hope yours is different outcome! He returned to vet, rec'd an allergy injection, first in his life, plus Penicillin x 10 days. However, the following side effects are seen in less than 1 dog in 10,000:mild and short-lived vomiting and diarrhoea as well as tremor (shaking), ataxia (inability to coordinate body movements) or convulsions. It was the first time she had taken Simparica. He was given fluids, anti-nausea meds, meds to assist with the inflammation of his esophagus. I have been giving my lab puppy (6 months old now) Simparica Trio since October. There are three drugs in the category of oral flea and tick preventives: UPDATE We had one normal day on Friday. FRIDAY, Sept. 21, 2018 (HealthDay News) -- Flea medicines protect your pet, but some animals can have serious side effects from products containing isoxazoline, U.S. health officials warn. No more itching but covered in same scabs. just gave my one year old dauchund her first dose of simparica My vet didnt tell me, We gave our Yorkie this and she went into seizures later in the day...what if any thing can be done. Hope all is well. 6 Pack is of $62.36, Simparica Chewables for Dogs above 88 lbs (Red) (I did mention the timing questioning the Simparica). There is a video on Facebook everyone who is thinking of using Simparica should see. Every good pet parent wants to keep fleas off his dog, but many worries about the side effects that can accompany various flea and tick treatments. For a full list of possible side effects, please see Adverse Reactions in the Patient Guide. So sorry! enable_page_level_ads: true Think long and hard before using this. I am keeping a close eye on her and will take her to the vet if she hasn’t improved by tonight. What is a good replacement? I went and picked her up today and all she does is lay around and drink water, turns her nose up at anything food related. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Sometimes, side effects are caused by two or more drugs reacting negatively together, Owen says, and you may not need both. This results in uncontrolled neuromuscular activity leading to death in insects or acarines. While there is a common list every person’s system reacts differently. I researched simparica after she started exhibiting problems and I have little doubt that this is what caused her problems. We had family in for the weekend and he was not himself. It is in the same class of toxin as Nexgard, and it works similarly. In a well‑controlled laboratory study, SIMPARICA TRIO began to kill fleas at 4 hours and demonstrated 100% effectiveness at 8 hours after initial administration. Simparica (sarolaner) was just introduced in March 2016. For a vet to still carry it after all the horrible press it’s gotten is just a glaring red flag: this vet is willfully ignoring a groundswell … The next day she had diarrhea. I gave the 1st one to my dog, 1st of this month. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrhea—both symptoms related to Fido’s digestive tract, rather than his nervous system. The reported side effects of both medications include vomiting, diarrhea, lethargy, and decreased appetite. I asked the vet what they recommended. Not wanting to play, shivering, and drinking excessively. I gave my dog his first dose today and 6 hours later he was throwing up and became frantic to get outside to eat grass. After about 2.5 weeks, she couldn't walk, bark, had tremors, didn't want to eat, and was so lethargic I thought we were going to lose her. I don’t want to add ANY stress to her system as she SEEMS to be on the road to recovery despite only 2 bm yesterday, at noon – normal. A few hours later, he began vomiting nonstop. This is referred to as conscious proprioception, awareness of body position & movement and ataxia, loss of body movements. It is better but not gone. My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. Good point, of course, Roger. Side effects after taking Sentinel for dogs are extremely rare. She passed away soon after taking this medication. I am very worried I called the vet they said oops sorry they made a mistake. so what about her puppies I am so worried. I called our Vet on the second day and they said they doubted very seriously that the Simparica would have give him diarrhea, and then told me that I should wait and see what happens with the next dose, because I had also told them that he had some drippings from some ground beef over his dog food the day before I gave him that first dose. No simparica for them either! We have given him pedialyte. Not known if there be permanent after-effects. We gave our 3.5 month old Aussie pup a dose of Simparica today (vet's prescription), and I did not see the warnings about giving it to dogs under 6 months. They did a blood test (this is literally 7 days later) and his ATL liver levels were off the charts at >2000. Your email address will not be published. If most side effects are mild, ( vomiting 12 hours later could be due to other things the dog has eaten within those 12 hours), I am ok with that. A week after I lost her I got COVID and was in the hospital for 20 days. 4 days no improvement, he said she probably got into something at the dog show and prescribed metronidazole. This was the first time she was given this drug and will be the last. How long does Simparica protection last? Could use of Simparica be related to increased prevalence of mast cell tumors in dogs? However, besides being nervous over the diarrhea, I am petrified about all of these people talking about seizures. Gave this flea medicine today and by 10 pm toy poodle having siesures every 3-10 seconds. Purchase for our girl ’ ’ these drugs in the first week of and. A new symptom may actually be a million to one problem three different kinds of ticks intestinal. S health care expert has recommended Simperica, but not full blown seizures are sensitive to the vet.. He just was n't the same had not shown any effects original so... 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